Muestra la distribución de disciplinas para esta publicación.
Publicaciones WoS (Ediciones: ISSHP, ISTP, AHCI, SSCI, SCI), Scopus, SciELO Chile.
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Año | 2020 | ||||||
Tipo | artículo de investigación |
Citas Totales
Autores Afiliación Chile
Instituciones Chile
% Participación
Internacional
Autores
Afiliación Extranjera
Instituciones
Extranjeras
ABSTRACT Araucaria araucana is a native conifer of Chile commonly called Araucaria. The knots of Araucaria are extremely hard wood and highly rot-resistant, they can be found in the forest decades after that the tree has dead and decomposed. Here we report the phytochemical characterization of different parts of the Araucaria as stemwood, branch and knots, founding a remarkable difference in the content of extractables in these parts, as well as the lignan composition, which is higher in knots than in branches or stemwood. Eudesmin was isolated and crystallized from organic extract of knots, its structure was determinate by NMR; moreover, secoisolariciresinol, lariciresinol and matairesinol were identified by GCMS and HPLC in contrast to standards, and quantified in stemwood, branch and knots. The results showed that secoisolariciresinol is the main lignan with 45.77 mg g−1, followed by eudesmin with 22.68 mg g−1, lariciresinol 4.57 mg g−1 and matairesinol with 1.19 mg g−1. The antioxidant activity in terms of DPPH assay showed that knotwood extract displays the higher activity, meanwhile that eudesmin did not displays activity in DPPH assay. The cytotoxic activity against SHSY5Y neuroblastoma and P3X myeloma cell lines, revelated a moderate activity of extracts, while eudesmin did not showed activity.
Ord. | Autor | Género | Institución - País |
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Bravo-Arrepol, Gaston | Hombre |
Universidad de Concepción - Chile
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Torres, Solange | Mujer |
Universidad de Concepción - Chile
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Figueroa, Fabian A. | Hombre |
Universidad de Concepción - Chile
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Perez, Claudia | Mujer |
Universidad de Concepción - Chile
Universidad de Concepción - Italia |
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PAZ-ROBLES, CRISTIAN FABIAN | Hombre |
Universidad de La Frontera - Chile
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Turchetti, Giovanni | Hombre |
Università degli Studi della Tuscia - Italia
Università degli Studi della Tuscia Viterbo - Italia Univ Tuscia - Italia |
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Tiezzi, Antonio | Hombre |
Università degli Studi della Tuscia - Italia
Università degli Studi della Tuscia Viterbo - Italia Univ Tuscia - Italia |
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Becerra, J | Hombre |
Universidad de Concepción - Chile
Universidad de Concepción - Italia |
Fuente |
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Comisión Nacional de Investigación Científica y Tecnológica |
CONICYT PIA/APOYO CCTE |
ANID |
National Agency for Research and Development |
National Agency for Research and Development (ANID -Chile) |
Agradecimiento |
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This work was funded by the National Agency for Research and Development (ANID -Chile) by the scholarship program “Doctorado Becas Chile” 21151154, Conicyt PIA/Apoyo CCTE AFB170007. We thanks to Héctor Sáez and Mario Cornejo from Los Alamos, Arauco for his assistance in the collection of the samples, and to Professor Roberto Rodríguez for the botanical characterization of samples. We also thank Dr. Carola Vergara and Francisca Narvaez for providing lignan standards. |
This work was funded by the National Agency for Research and Development (ANID -Chile) by the scholarship program "Doctorado Becas Chile" 21151154, Conicyt PIA/Apoyo CCTE AFB170007. We thanks to Hector Saez and Mario Cornejo from Los Alamos, Arauco for his assistance in the collection of the samples, and to Professor Roberto Rodriguez for the botanical characterization of samples. We also thank Dr. Carola Vergara and Francisca Narvaez for providing lignan standards. |