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DOI | 10.1186/1471-2164-15-869 | ||||
Año | 2014 | ||||
Tipo | artículo de investigación |
Citas Totales
Autores Afiliación Chile
Instituciones Chile
% Participación
Internacional
Autores
Afiliación Extranjera
Instituciones
Extranjeras
Conclusions: Here we present a comprehensive characterization of alpha-keratin genes among mammals and elucidate the mechanisms involved in the evolution of this gene family. We identified lineage-specific gene duplications and gene loss among the Laurasiatherian and Euarchontoglires species included in the study. Interestingly, cetaceans present an increased loss of hair-type keratin genes when compared to other terrestrial mammals. As suggested by the 'less is more' hypothesis, we do not rule out the possibility that the gene loss of hair-type keratin genes in these species might be associated to the hairless phenotype and could have been adaptive in response to new selective pressures imposed by the colonization of a new habitat. Our study provides support for the idea that pseudogenes are not simply 'genomic fossils' but instead have adaptive roles during the evolutionary process.
Ord. | Autor | Género | Institución - País |
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1 | FREITAS-NERY, Mariana Freitas | Mujer |
Universidad Austral de Chile - Chile
UNIV SAO PAULO - Brasil Universidade de Sao Paulo - USP - Brasil Universidade de São Paulo - Brasil |
2 | Arroyo, Jose Ignacio | Hombre |
Universidad Austral de Chile - Chile
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2 | Arroyo, José I. | Hombre |
Universidad Austral de Chile - Chile
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3 | Opazo, Juan C. | Hombre |
Universidad Austral de Chile - Chile
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Fuente |
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Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT) |
Fondo Nacional de Desarrollo Científico y Tecnológico |
CONICYT Doctoral Fellowship |
Agradecimiento |
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This study was funded by a grant form the Fondo Nacional de Desarrollo Cientifico y Tecnologico (FONDECYT 1120032). MFN and JIA hold a CONICYT doctoral fellowship. |
This study was funded by a grant form the Fondo Nacional de Desarrollo Cientifico y Tecnologico (FONDECYT 1120032). MFN and JIA hold a CONICYT doctoral fellowship. |