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DOI | 10.1039/C3BM60185D | ||||
Año | 2014 | ||||
Tipo | artículo de investigación |
Citas Totales
Autores Afiliación Chile
Instituciones Chile
% Participación
Internacional
Autores
Afiliación Extranjera
Instituciones
Extranjeras
The present scientific research resulted in the development of novel microbial resistant inorganic nanocomposite hydrogels, which can be used as antibacterial agents. They are promising candidates for advanced antimicrobial applications in the field of biomedical science. Novel inorganic nanocomposite hydrogels were developed from Carbopol (R) 980 NF and acrylamide. Dual-metallic (Ag-0-Au-0) nanoparticles were prepared (via a green process) by the nucleation of silver and gold salts with mint leaf extract to form a hydrogel network. The Carbopol nanocomposite hydrogels contain (Ag-0-Au-0) nanoparticles similar to 5 +/- 3 nm in size, which was confirmed by transmission electron microscopy. The developed hydrogels were characterized using Fourier transform infrared (FTIR) spectroscopy, thermo-gravimetric analysis (TGA), scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS) and transmission electron microscopy (TEM). The pure and inorganic nanocomposite hydrogels developed were tested against Bacillus and E. coli, for their antibacterial properties. The results indicate that the inorganic nanocomposites show significantly greater antimicrobial activity than the pure hydrogels. Therefore, novel microbial resistant Carbopol nanocomposite hydrogels can be used as potential candidates for antibacterial applications.
Ord. | Autor | Género | Institución - País |
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1 | Varaprasad, Kokkarachedu | - |
Universidad de Concepción - Chile
Tshwane Univ Technol - República de Sudáfrica Tshwane University of Technology - República de Sudáfrica |
2 | Reddy, G. Siva Mohan | - |
Tshwane Univ Technol - República de Sudáfrica
Tshwane University of Technology - República de Sudáfrica |
3 | Jayaramudu, Jaragula | - |
Tshwane Univ Technol - República de Sudáfrica
Tshwane University of Technology - República de Sudáfrica |
4 | Sadiku, Rotimi | Hombre |
Tshwane Univ Technol - República de Sudáfrica
Tshwane University of Technology - República de Sudáfrica |
5 | Ramam, K. V.S. | - |
Universidad de Concepción - Chile
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6 | Ray, S. Sinha | - |
CSIR - República de Sudáfrica
The Council for Scientific and Industrial Research - República de Sudáfrica |